The timing of Start is determined primarily by increased synthesis of the Cln3 activator rather than dilution of the Whi5 inhibitor

Athanasios Litsios; Pooja Goswami; Hanna M Terpstra; Carleton Coffin; Luc-Alban Vuillemenot; Mattia Rovetta; Ghada Ghazal; Paolo Guerra; Katarzyna Buczak; Alexander Schmidt; Sylvain Tollis; Mike Tyers; Catherine A Royer; Andreas Milias-Argeitis; Matthias Heinemann

doi:10.1091/mbc.E21-07-0349

The timing of Start is determined primarily by increased synthesis of the Cln3 activator rather than dilution of the Whi5 inhibitor

Athanasios Litsios, Pooja Goswami, Hanna M Terpstra, Carleton Coffin, Luc-Alban Vuillemenot, Mattia Rovetta, Ghada Ghazal, Paolo Guerra, Katarzyna Buczak, Alexander Schmidt, Sylvain Tollis^*, Mike Tyers^*, Catherine A Royer^*, Andreas Milias-Argeitis^*, Matthias Heinemann^*

^*Corresponding author voor dit werk

Molecular Systems Biology

Onderzoeksoutput › Academic › peer review

9 Citaten (Scopus)

197 Downloads (Pure)

Originele taal-2	English
Artikelnummer	rp2
Aantal pagina's	14
Tijdschrift	Molecular Biology of the Cell
Volume	33
Nummer van het tijdschrift	5
DOI's	https://doi.org/10.1091/mbc.E21-07-0349
Status	Published - 1-mei-2022

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10.1091/mbc.E21-07-0349

The timing of Start is determined primarily by increased synthesis of the Cln3 activator rather than dilution of the Whi5 inhibitorFinal publisher's version, 2,02 MBLicentie: CC BY

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Dataset Figure_4: Nuclear Whi5-GFP intensity versus time from repeated imaging of the same individual cells
Litsios, A. (Contributor), Goswami, P. (Contributor), Terpstra, H. (Contributor), Coffin, C. (Contributor), Vuillemenot, L.-A. P. E. (Contributor), Rovetta, M. (Contributor), Ghazal, G. (Contributor), Guerra, P. (Contributor), Buczak, K. (Contributor), Schmidt, A. (Contributor), Tollis, S. (Contributor), Tyers, M. (Contributor), Royer, C. A. (Contributor), Milias-Argeitis, A. (Contributor) & Heinemann, M. (Contributor), DataverseNL, 21-feb.-2022
DOI: 10.34894/ivwack
Dataset
Dataset Figure_2: Determination of nuclear Whi5 concentration by widefield fluorescence microscopy is confounded by non-proportional scaling of the nuclear-to-cell volume
Litsios, A. (Contributor), Goswami, P. (Contributor), Terpstra, H. (Contributor), Coffin, C. (Contributor), Vuillemenot, L.-A. P. E. (Contributor), Rovetta, M. (Contributor), Ghazal, G. (Contributor), Guerra, P. (Contributor), Buczak, K. (Contributor), Schmidt, A. (Contributor), Tollis, S. (Contributor), Tyers, M. (Contributor), Royer, C. A. (Contributor), Milias-Argeitis, A. (Contributor) & Heinemann, M. (Contributor), DataverseNL, 24-feb.-2022
DOI: 10.34894/tfc012
Dataset
Dataset Figure_5: Whi5-GFP intensity versus size and time in a synchronous G1 population
Litsios, A. (Contributor), Goswami, P. (Contributor), Terpstra, H. (Contributor), Coffin, C. (Contributor), Vuillemenot, L.-A. P. E. (Contributor), Rovetta, M. (Contributor), Ghazal, G. (Contributor), Guerra, P. (Contributor), Buczak, K. (Contributor), Schmidt, A. (Contributor), Tollis, S. (Contributor), Tyers, M. (Contributor), Royer, C. A. (Contributor), Milias-Argeitis, A. (Contributor) & Heinemann, M. (Contributor), DataverseNL, 21-feb.-2022
DOI: 10.34894/hnwbym
Dataset

Citeer dit

Litsios, A., Goswami, P., Terpstra, H. M., Coffin, C., Vuillemenot, L.-A., Rovetta, M., Ghazal, G., Guerra, P., Buczak, K., Schmidt, A., Tollis, S., Tyers, M., Royer, C. A., Milias-Argeitis, A., & Heinemann, M. (2022). The timing of Start is determined primarily by increased synthesis of the Cln3 activator rather than dilution of the Whi5 inhibitor. Molecular Biology of the Cell, 33(5), Artikel rp2. https://doi.org/10.1091/mbc.E21-07-0349

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title = "The timing of Start is determined primarily by increased synthesis of the Cln3 activator rather than dilution of the Whi5 inhibitor",

author = "Athanasios Litsios and Pooja Goswami and Terpstra, {Hanna M} and Carleton Coffin and Luc-Alban Vuillemenot and Mattia Rovetta and Ghada Ghazal and Paolo Guerra and Katarzyna Buczak and Alexander Schmidt and Sylvain Tollis and Mike Tyers and Royer, {Catherine A} and Andreas Milias-Argeitis and Matthias Heinemann",

year = "2022",

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Litsios, A, Goswami, P, Terpstra, HM, Coffin, C, Vuillemenot, L-A, Rovetta, M, Ghazal, G, Guerra, P, Buczak, K, Schmidt, A, Tollis, S, Tyers, M, Royer, CA, Milias-Argeitis, A & Heinemann, M 2022, 'The timing of Start is determined primarily by increased synthesis of the Cln3 activator rather than dilution of the Whi5 inhibitor', Molecular Biology of the Cell, vol. 33, nr. 5, rp2. https://doi.org/10.1091/mbc.E21-07-0349

TY - JOUR

T1 - The timing of Start is determined primarily by increased synthesis of the Cln3 activator rather than dilution of the Whi5 inhibitor

AU - Litsios, Athanasios

AU - Goswami, Pooja

AU - Terpstra, Hanna M

AU - Coffin, Carleton

AU - Vuillemenot, Luc-Alban

AU - Rovetta, Mattia

AU - Ghazal, Ghada

AU - Guerra, Paolo

AU - Buczak, Katarzyna

AU - Schmidt, Alexander

AU - Tollis, Sylvain

AU - Tyers, Mike

AU - Royer, Catherine A

AU - Milias-Argeitis, Andreas

AU - Heinemann, Matthias

PY - 2022/5/1

Y1 - 2022/5/1

U2 - 10.1091/mbc.E21-07-0349

DO - 10.1091/mbc.E21-07-0349

M3 - Comment/Letter to the editor

C2 - 35482514

SN - 1059-1524

VL - 33

JO - Molecular Biology of the Cell

JF - Molecular Biology of the Cell

IS - 5

M1 - rp2

ER -

The timing of Start is determined primarily by increased synthesis of the Cln3 activator rather than dilution of the Whi5 inhibitor

Toegang tot document

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Datasets

Dataset Figure_4: Nuclear Whi5-GFP intensity versus time from repeated imaging of the same individual cells

Dataset Figure_2: Determination of nuclear Whi5 concentration by widefield fluorescence microscopy is confounded by non-proportional scaling of the nuclear-to-cell volume

Dataset Figure_5: Whi5-GFP intensity versus size and time in a synchronous G1 population

Citeer dit