Tritylamine as an Ammonia Surrogate in the Ugi Tetrazole Synthesis

Ting Zhao, Andre Boltjes, Eberhardt Herdtweck, Alexander Doemling*

*Bijbehorende auteur voor dit werk

OnderzoeksoutputAcademicpeer review

47 Citaten (Scopus)


The role of tritylamine is introduced as a convenient ammonia substitute in the Ugi tetrazole synthesis. Fifteen examples and their mild cleavage products are described In satisfactory to good yields. N-Unsubstituted alpha-aminotetrazoles are important compounds with annotated biological activities, and the described two-step synthesis provided an alternative route to otherwise difficult to access derivatives.

Originele taal-2English
Pagina's (van-tot)639-641
Aantal pagina's3
TijdschriftOrganic letters
Nummer van het tijdschrift3
StatusPublished - 1-feb.-2013

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