Tunable Size- and Charge-based Particle Chromatography Using Time-varying Voltage Gradients

Sergio Fernandez Poza, Patty Mulder, Elisabeth Verpoorte

OnderzoeksoutputAcademic

1 Citaat (Scopus)

Samenvatting

Here we present for the first time the implementation of Flow-Induced Electrokinetic Trapping (FIET) for the quantitative separation of polymer microparticles in microfluidic channels. FIET is a particle-trapping mechanism that depends on the generation of recirculating flows in non-uniform microchannels. Polymer microspheres captured in recirculating flows can be separated based on differences in charge and size, leading to a chip-based separation technique called tunable hydrodynamic chromatography (THC). We have harnessed FIET to realize a new methodology for particle separation. Quantitative separations (≥99%) of microspheres have been achieved within less than 10 minutes.
Originele taal-2English
TitelThe 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences
Pagina's1547-1548
StatusPublished - 12-okt.-2016
EvenementThe 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences - Dublin, Ireland
Duur: 9-okt.-201613-okt.-2016

Conference

ConferenceThe 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences
Land/RegioIreland
StadDublin
Periode09/10/201613/10/2016

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