TY - JOUR
T1 - Two cases with postural axial tremor
T2 - Consider a genetic origin
AU - Zutt, R
AU - Elting, J W
AU - Santens, P
AU - Luijckx, G J R
AU - Tijssen, M A J
N1 - Copyright © 2020 Elsevier Ltd. All rights reserved.
PY - 2020/8
Y1 - 2020/8
N2 - We present two cases with postural axial tremor predominantly involving the head, trunk, and shoulders. In the first patient, the postural tremor occurred in multiple attacks a day lasting approximately 10 min. The second patient developed a progressive tremor of his head and arms, worsened during sitting and standing. Electrophysiological supported the postural axial tremor in both patients with a varying 3-10 Hz tremor frequency between different muscles and within the same muscles at different times. Postural axial tremor is a rare and complex movement disorder. The majority of cases are caused by acquired cerebellar pathology. However, isolated cases with underlying genetic disorders are described in literature. Here, we illustrate how to differentiate paroxysmal axial tremor from other axial hyperkinetic movement disorders and extend the genetic heterogeneity of this intriguing movement disorder phenotype.
AB - We present two cases with postural axial tremor predominantly involving the head, trunk, and shoulders. In the first patient, the postural tremor occurred in multiple attacks a day lasting approximately 10 min. The second patient developed a progressive tremor of his head and arms, worsened during sitting and standing. Electrophysiological supported the postural axial tremor in both patients with a varying 3-10 Hz tremor frequency between different muscles and within the same muscles at different times. Postural axial tremor is a rare and complex movement disorder. The majority of cases are caused by acquired cerebellar pathology. However, isolated cases with underlying genetic disorders are described in literature. Here, we illustrate how to differentiate paroxysmal axial tremor from other axial hyperkinetic movement disorders and extend the genetic heterogeneity of this intriguing movement disorder phenotype.
U2 - 10.1016/j.parkreldis.2020.04.013
DO - 10.1016/j.parkreldis.2020.04.013
M3 - Article
C2 - 33023723
SN - 1353-8020
VL - 77
SP - 152
EP - 154
JO - Parkinsonism & Related Disorders
JF - Parkinsonism & Related Disorders
ER -