Two-Step, One-Pot Synthesis of Visible-Light-Responsive 6-Azopurines

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The first general two-step, one-pot syntheticroute to 6-azopurines is presented. Microwave-assistednucleophilic aromatic substitution of protected 6-chloropurineswith hydrazines or hydrazides, followed by metal-free oxidationwith oxygen, gives 6-azopurines in high to excellent yields.Photophysical studies revealed intensive n−π* absorption bandthat makes trans-to-cis photoswitching possible using visiblelight (λ = 530 nm).

Originele taal-2English
Pagina's (van-tot)5090-5093
Aantal pagina's4
TijdschriftOrganic letters
Nummer van het tijdschrift19
StatusPublished - 6-okt-2017

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