Visualization of Decision Tree State for the Classification of Parkinson's Disease

David Williams, Deborah Mudali, Hugo Buddelmeijer, Parisa Noorishad, Sanne Meles, Remco Renken, Klaus Leenders, E Valentijn, Johannes Roerdink

OnderzoeksoutputAcademicpeer review


Decision trees have been shown to be effective at classifying subjects with Parkinson's disease when provided with features (subject scores) derived from FDG-PET data. Such subject scores have strong discriminative power but are not intuitive to understand. We therefore augment each decision node with thumbnails of the principal component (PC) images from which the subject scores are computed, and also provide labeled scatter plots of the distribution of scores. These plots allow the progress of individual subjects to be traced through the tree and enable the user to focus on complex or unexpected classifications. In addition, we present a visual representation of a typical brain activity pattern arriving at each leaf node, and show how this can be compared to a known reference to validate the behaviour of the tree.
Originele taal-2English
Pagina's (van-tot)25-41
Aantal pagina's25
TijdschriftJournal of Biomedical Engineering and Medical Imaging
Nummer van het tijdschrift3
StatusPublished - 1-aug-2016

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