Young People's Experiences of Participation in Clinical Trials: Reasons for Taking Part

Malou Luchtenberg*, Els Maeckelberghe, Louise Locock, Lesley Powell, A. A. Eduard Verhagen

*Bijbehorende auteur voor dit werk

    OnderzoeksoutputAcademicpeer review

    35 Citaten (Scopus)


    Given the lack of knowledge about safety and efficacy of many treatments for children, pediatric clinical trials are important, but recruitment for pediatric research is difficult. Little is known about children's perspective on participating in trials. The purpose of this study was to understand the experiences and motivations of young people who took part in clinical trials. This is a qualitative interview study of 25 young people aged 10-23 who were invited to take part in clinical trials. Interviews were audio or video recorded and analyzed using framework analysis. Young peoples' motivations were both personal benefit and helping others. Both incentives appeared to be more complex than expected. We introduce the terms network of exchange and intergenerational solidarity to describe these motivations. To improve recruitment, professionals should be more open about research opportunities, provide better information, and give young people feedback after the trial has ended.

    Originele taal-2English
    Pagina's (van-tot)3-13
    Aantal pagina's11
    TijdschriftAmerican journal of bioethics
    Nummer van het tijdschrift11
    StatusPublished - 2-nov.-2015

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